Scientific Image Gallery
Platelet satellitosis is a rare phenomenon of platelets aggregating around polymorphonuclear white blood cells. It appears to be induced or enhanced by the presence of EDTA, a commonly used anticoagulant, and is not associated with any definite disease process.
<p>Platelet satellitosis is a rare phenomenon of platelets aggregating around polymorphonuclear white blood cells. It appears to be induced or enhanced by the presence of EDTA, a commonly used anticoagulant, and is not associated with any definite disease process.</p>
Platelet satellitosis is a rare phenomenon of platelets aggregating around polymorphonuclear white blood cells. It appears to be induced or enhanced by the presence of EDTA, a commonly used anticoagulant, and is not associated with any definite disease process.
<p>Platelet satellitosis is a rare phenomenon of platelets aggregating around polymorphonuclear white blood cells. It appears to be induced or enhanced by the presence of EDTA, a commonly used anticoagulant, and is not associated with any definite disease process.</p>
Inconspicuous number and size of platelets in a healthy individual.
<p>Inconspicuous number and size of platelets in a healthy individual.</p>
Artefact (pollen).
<p>Artefact (pollen).</p>
In primary myelofibrosis (PMF, also called chronic idiopathic myelofibrosis, CIMF) nuclei of megakaryocytes can be detected in the peripheral blood (May-Grünwald-Giemsa stain) and rarely, like here, small megakaryocytes. Both derive from extramedullary haematopoiesis.
<p>In primary myelofibrosis (PMF, also called chronic idiopathic myelofibrosis, CIMF) nuclei of megakaryocytes can be detected in the peripheral blood (May-Grünwald-Giemsa stain) and rarely, like here, small megakaryocytes. Both derive from extramedullary haematopoiesis.</p>
In the bone marrow histology the reticular fibres in PMF (alo called CIMF) can be identified by their black colour (Gomori stain).
<p>In the bone marrow histology the reticular fibres in PMF (alo called CIMF) can be identified by their black colour (Gomori stain). </p>
PMF (also called CIMF) in the fibrotic stage with a leucoerythroblastic blood picture (May-Grünwald-Giemsa stain): In this patient immature granulocytes, erythroblasts and many teardrop cells (->) were found. In the fibrotic stage there is usually anaemia present and a low to normal or reduced platelet count. Myeloblasts might be present. But more than 10% already indicate blast cell excess or transition into AML.
<p>PMF (also called CIMF) in the fibrotic stage with a leucoerythroblastic blood picture (May-Grünwald-Giemsa stain): In this patient immature granulocytes, erythroblasts and many teardrop cells (->) were found. In the fibrotic stage there is usually anaemia present and a low to normal or reduced platelet count. Myeloblasts might be present. But more than 10% already indicate blast cell excess or transition into AML. </p>
This peripheral blood film (May-Grünwald-Giemsa stain) is from a patient with PMF (also called CIMF) in the prefibrotic stage. You can see scattered teardrop cells (->). Furthermore, a few granulocytic precursors and very few erythroblasts were detected (not shown). The automated cell count showed slight leukocytosis, thrombocytosis and anaemia.
<p>This peripheral blood film (May-Grünwald-Giemsa stain) is from a patient with PMF (also called CIMF) in the prefibrotic stage. You can see scattered teardrop cells (->). Furthermore, a few granulocytic precursors and very few erythroblasts were detected (not shown). The automated cell count showed slight leukocytosis, thrombocytosis and anaemia.</p>
Cell description:
Size: 10-18 µm, smaller than lymphoblast
Nucleus: round with coarser structure than a lymphoblast, one distinct nucleolus
Cytoplasm: blue without granules
<p>Cell description: </p> <p>Size: 10-18 µm, smaller than lymphoblast </p> <p>Nucleus: round with coarser structure than a lymphoblast, one distinct nucleolus </p> <p> Cytoplasm: blue without granules </p>